ClinicalTrials.gov

Tracking AI in medicine — clinical trials

From the U.S. NIH clinical-trial registry ClinicalTrials.gov, clinical trials of AI (artificial intelligence / machine learning) in medicine and diagnostics, organized with conditions, sponsor, and status. This site is not an official U.S. government website.

This page organizes public data and is not medical advice or diagnosis. Decisions such as trial participation should be based on your physician and official information. We do not handle individual patient data.

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Featured

Notable AI medical trials explained with key points, FAQs, and sources.

Recruiting Genetic Conditions

AI medical trial: a natural-history study collecting medical data on genetic conditions to build "advanced data analytics" (AI) tools (NHGRI observational study) — a clinical trial (ClinicalTrials.gov)

National Human Genome Research Institute (NHGRI)

A natural-history (observational) study collecting medical and genetic data from people with (or suspected to have) genetic conditions, and their relatives. The data aims to help develop advanced data-analytics tools for better analyzing and understanding genetic data.

Active, not recruiting Lung Cancer / Breast Cancer

AI medical trial: AstraZeneca evaluates "AI pathology" in real-world lung and breast cancer practice (multinational, observational)

AstraZeneca

A multinational observational study by AstraZeneca evaluating how computational pathology plus AI algorithms are used in the pathology workup of patients with suspected lung and breast cancer — gauging how far AI has entered routine pathology.

Recruiting Graves Disease / Hyperthyroidism/Thyrotoxicosis

AI medical trial: detecting thyrotoxicosis from consumer-wearable heart rate with AI (Thyroscope, Glandy HYPER)

THYROSCOPE INC.

An observational study evaluating whether the AI software device "Glandy HYPER" can detect a thyrotoxic state in hyperthyroidism (Graves' disease) using heart-rate data from commercial wearables, correlated with thyroid function tests (free T4).

Recruiting Ventricular Ejection Fraction / LVF

AI medical trial: estimating ejection fraction (EF) from a wearable ECG with AI (Peerbridge, heart-failure screening)

Peerbridge Health, Inc

A multicenter trial by Peerbridge Health validating an investigational AI Software-as-a-Medical-Device that estimates ejection fraction (EF) severity from continuous ECG captured by an FDA-cleared wearable patch, compared against echocardiography.

Completed Pneumothorax / Pulmonary Nodule, Solitary

AI medical trial: "Carebot AI CXR" reads chest X-rays vs. radiologists (completed)

Carebot s.r.o.

A multi-reader retrospective study evaluating how accurately the AI chest X-ray tool "Carebot AI CXR" (a deep-learning automated detection system) detects findings such as pneumothorax, pulmonary nodules, atelectasis, cardiomegaly, and pleural effusion compared with individual radiologists. Completed with 956 cases.

Recruiting Infertility (IVF Patients) / ICSI

Development of an AI Platform to Analyze Sperm and Predict Their Clinical Potential — a clinical trial (ClinicalTrials.gov)

Fecundis Lab SL

A multicenter observational study (no intervention) that aims to develop an AI platform for analyzing semen samples and predicting their clinical potential.

Recruiting Arrhythmia / Long QT Syndrome

AI ECG Analysis to Predict Deadly Arrhythmias and ICI Myocarditis (ELDORA) — a clinical trial (ClinicalTrials.gov)

Groupe Hospitalier Pitie-Salpetriere

A non-interventional observational study that aims to develop and validate interpretable AI tools applied to electrocardiogram (ECG) data for predicting life-threatening arrhythmias and immune checkpoint inhibitor-related myocarditis.

Completed Pregnancy Complications

Estimating fetal weight from ultrasound — AI vs. the standard Hadlock method — a clinical trial (ClinicalTrials.gov)

Copenhagen Academy for Medical Education and Simulation

An observational study comparing the accuracy of two AI models with the traditional Hadlock formula for estimating fetal weight from ultrasound scans at 24–42 weeks of gestation.

Completed Iatrogenesis / Clinical Vignettes

Evaluating the AI App "POSOS" for Detecting Drug-Induced Iatrogenesis (A Clinical Vignettes Study) — a clinical trial (ClinicalTrials.gov)

Centre Hospitalier Universitaire, Amiens

A multicenter observational study using simulated cases (clinical vignettes) to test how much the AI app "POSOS" helps physicians detect drug-induced iatrogenesis.

Not yet recruiting Healthy Volunteer

Using AI to Uncover What Drives How Much We Eat — a clinical trial (ClinicalTrials.gov)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

An observational study that measures healthy adults extensively over two years and applies AI to understand why people differ in their tendency to gain weight.

Enrolling by invitation Esophageal Cancer

Observational study testing the clinical utility of an AI large language model for esophageal cancer screening, diagnosis, treatment and prognosis — a clinical trial (ClinicalTrials.gov)

The First Affiliated Hospital of Henan University of Science and Technology

An observational study using de-identified data from patients in routine esophageal cancer care to test whether an AI large language model can improve early detection, diagnostic accuracy, treatment personalization and prognosis prediction versus standard care over three years.

Not yet recruiting Cardiac Amyloidosis / Heart Failure With Preserved Ejection Fraction (HFPEF)

AI medical trial: AI echocardiography to detect cardiac amyloidosis — a clinical trial (ClinicalTrials.gov)

Germans Trias i Pujol Hospital

A prospective study testing whether AI applied to echocardiography images can pick up patients with findings suggestive of cardiac amyloidosis (especially the ATTR type) — a condition easily missed. The AI flags are checked against confirmatory methods: bone-tracer SPECT, cardiac MRI, and blood tests.

Latest (original, AI-in-medicine)

Recent clinical trials

Recently updated AI-in-medicine trials (original titles). Each links to the official ClinicalTrials.gov page.

Recruiting Observational Study of Advanced Data Analytics in Genetic Conditions National Human Genome Research Institute (NHGRI) ・ Genetic Conditions
Recruiting A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drug... National Cancer Institute (NCI) ・ Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Active, not recruiting Biomechanical Characterisation of 3D Printed Comfort Insoles University of Pecs ・ Healthy
Recruiting Evaluating an AI-Based Mobile Application for Chemotherapy Support in Breast Cancer... Dena h. Al-Tameemi ・ Breast Cancer / Breast Neoplasm
Not yet recruiting BELLRICU PROJECT: Precision Medicine in Respiratory Intermediate Care Units Hospital Universitari de Bellvitge ・ Acute Respiratory Failure (ARF) / Intermediate Respiratory Care Unit
Not yet recruiting AI-Assisted Chest-CT Reporting for Enhanced Speed and Quality (The DOUBLE-ACE Study) Shanghai Zhongshan Hospital ・ Thoracic Diseases / Chest CT Scan
Recruiting The Rule-Out Acute Myocardial Infarction Using Aritifical Intelligence Electrocardio... CHA University ・ Myocardial Infarction (MI) / Chest Pain Rule Out Myocardial Infarction
Recruiting Diagnostic Trial of a Vision Transformer-Based Ultrasound AI Model for Placenta Accr... FANG HE ・ Placenta Accreta Spectrum
Not yet recruiting Artificial Intelligence-Assisted Lesion-Based Urgent Referral Triage of Ultra-Widefi... Xiamen Ophthalmology Center Affiliated to Xiamen University ・ Vision-Threatening Retinal Lesions / Urgent Referral Retinal Findings
Recruiting Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy Photocure ・ Bladder Cancer / Non-muscle Invasive Bladder Cancer
Completed Cluster-Set vs. Traditional-Set Plyometric Loading in Tennis Players Uludag University ・ Plyometric Training
Recruiting Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia W... Mayo Clinic ・ Endometrial Carcinoma
Active, not recruiting AI-THEROSCOPE: AI Detection of Subclinical Atherosclerosis From Retinal Images Infanta Leonor University Hospital ・ Subclinical Atherosclerosis / Cardiovascular Risk
Not yet recruiting Efficacy Evaluation of Intelligent Rehabilitation Programs Based on AI-Powered Digit... Peking University Third Hospital ・ Articular / Range of Motion
Not yet recruiting Parent-led Assessment and Recognition of AOM Using Digital Ear Imaging Turku University Hospital ・ Acute Otitis Media / Otitis Media
Recruiting AI ECG Algorithm for Detecting LV Systolic Dysfunction Ajou University School of Medicine ・ HF - Heart Failure
Recruiting Virtual Intelligence for Transformative Lifestyle Solutions in Pain Montefiore Medical Center ・ Chronic Pain
Not yet recruiting Artificial Intelligence Versus Clinical Examination in White Spot Lesions Detection,... Cairo University ・ White Spot Lesion of Tooth
Recruiting DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adole... Adhera Health, Inc. ・ Type 1 Diabetes / T1D
Recruiting Construction and Clinical Validation of a Predictive Model for Postoperative Adjuvan... Second Affiliated Hospital, School of Medicine, Zhejiang University ・ Hepatocellular Carcinoma (HCC) / Artificial Intelligent
Completed Machine Learning Model for Predicting Recovery After Critical Illness Hospital de Clinicas de Porto Alegre ・ Funcional Status / Return to Work
Recruiting AI-Assisted Relaxation and Breathing Training in Postmenopausal Women Baskent University ・ Postmenopausal Period / Postmenopausal Women
Not yet recruiting Artificial Intelligence-based Dietary Care System National Taiwan University Hospital ・ AI Care Device
Completed AI-assisted GNW on Adolescent Emotional Distress Peking University ・ Emotional Disturbance / Emotional Regulation
Recruiting AIM-IBD: A Microbiome-Targeted Supplement in Mild-to-Moderate Ulcerative Colitis ENBIOSIS BIOTECHNOLOGIES ・ Ulcerative Colitis (UC) / Inflammatory Bowel Disease (IBD)
Recruiting ANCHOR Validation Trial in High-Risk Multidisciplinary Care Waymark ・ High-Risk Multidisciplinary Care / Clinical Decision Support
Not yet recruiting Multimodal Glucose Prediction in Type 2 Diabetes Johns Hopkins University ・ Type 2 Diabetes
Not yet recruiting The LalelaLung Study: Digital Stethoscope Clinical Evaluation Johns Hopkins University ・ Pneumonia / Tuberculosis, Pulmonary
Not yet recruiting AI Algorithm-Informed Biopsy for Prostate Cancer Detection With Indeterminate and Lo... University of Arkansas ・ Prostate Cancer
Active, not recruiting Testing an AI Large Language Model Tool for Cognitive Debiasing in Musculoskeletal C... University of Texas at Austin ・ Any Chronic, Non-traumatic Orthopedic Condition

Source: ClinicalTrials.gov (U.S. NIH/NLM, public domain). This site does not provide medical advice. Verify the latest and exact details with the official source. This site is not endorsed or certified by the NIH/NLM.