What the data shows
- In FY2026, the largest single NIH research award shown here is about ≈$56.6M to NATIONAL OPINION RESEARCH CENTER (NIH Office of the Director).
- The top 60 awards here total about ≈$1.37B — concentrated in large clinical networks, research centers, and infrastructure (data, biobanks, vaccine facilities).
- NIH funds on the order of tens of thousands of projects a year; this page shows only the largest by fiscal-year funding. For who wins the most overall, see the institution ranking.
NIH and its 27 Institutes & Centers (ICs)
NIH is the world's largest public biomedical research agency, funding on the order of tens of thousands of projects a year. It is organized into 27 Institutes and Centers (ICs) by disease and field — e.g., the National Cancer Institute (NCI), the National Institute of Allergy and Infectious Diseases (NIAID), the National Heart, Lung, and Blood Institute (NHLBI) — so the funding IC signals a project's focus area. Funding is mostly competitive extramural awards to universities and medical schools; this page shows those with the largest fiscal-year funding.
Largest research projects by award (FY2026)
| # | Project (official page ↗) | Institution | Funding IC | FY award |
|---|---|---|---|---|
| 1 | Partnering for Precision Medicine: A Collaborative Services Center for the All of Us Program OT2OD036464 | NATIONAL OPINION RESEARCH CENTER (IL) | NIH Office of the Director | ≈$56.6M |
| 2 | NHLBI Community Engagement Technical Assistance Center (CETAC) OT2HL158287 | WESTAT, INC. (MD) | National Heart Lung and Blood Institute | ≈$41.1M |
| 3 | HIV Prevention Trials Network Leadership and Operations Center UM1AI068619 | FAMILY HEALTH INTERNATIONAL (NC) | National Institute of Allergy and Infectious Diseases | ≈$39.6M |
| 4 | Biomedical Information Technology, Software Development, and Informatics Support CO25001001- | NATIONAL CANCER INSTITUTE | National Cancer Institute | ≈$36.2M |
| 5 | Leadership and Operations Center (LOC), AIDS Clinical Trials Group UM1AI068636 | UNIV OF NORTH CAROLINA CHAPEL HILL (NC) | National Institute of Allergy and Infectious Diseases | ≈$34.7M |
| 6 | HIV Vaccines Clinical Trials Network Leadership and Operations Center UM1AI068614 | FRED HUTCHINSON CANCER CENTER (WA) | National Institute of Allergy and Infectious Diseases | ≈$33.1M |
| 7 | The Health & Aging Brain Study - Health Disparities (HABS-HD) U19AG078109 | UNIVERSITY OF NORTH TEXAS HLTH SCI CTR (TX) | National Institute on Aging | ≈$33M |
| 8 | Health and Retirement Study: Yrs 35-40 U01AG009740 | UNIVERSITY OF MICHIGAN AT ANN ARBOR (MI) | National Institute on Aging | ≈$32.5M |
| 9 | Defining Evidence for Programs to Ensure Nutrition for Development (DEPEND) Coordinating Center OT2OD043072 | RESEARCH TRIANGLE INSTITUTE (NC) | NIH Office of the Director | ≈$32.5M |
| 10 | SDMC: HIV Vaccine Trials Network UM1AI068635 | FRED HUTCHINSON CANCER CENTER (WA) | National Institute of Allergy and Infectious Diseases | ≈$30.8M |
| 11 | Alzheimer's Clinical Trials Consortium (ACTC) U24AG057437 | UNIVERSITY OF SOUTHERN CALIFORNIA (CA) | National Institute on Aging | ≈$30.4M |
| 12 | ADRC Consortium for Clarity in ADRD Research Through Imaging U01AG082350 | UNIVERSITY OF WISCONSIN-MADISON (WI) | National Institute on Aging | ≈$29.6M |
| 13 | HIV Vaccine Trials Network Laboratory Center UM1AI068618 | FRED HUTCHINSON CANCER CENTER (WA) | National Institute of Allergy and Infectious Diseases | ≈$29.1M |
| 14 | Immune Tolerance Network UM1AI109565 | BENAROYA RESEARCH INST AT VIRGINIA MASON (WA) | National Institute of Allergy and Infectious Diseases | ≈$28.5M |
| 15 | COG NCTN Network Group Operations Center U10CA180886 | COG RESEARCH FOUNDATION, LLC (CA) | National Cancer Institute | ≈$28.4M |
| 16 | Data Coordinating Center for Type 1 Diabetes TrialNet U01DK106993 | UNIVERSITY OF SOUTH FLORIDA (FL) | National Institute of Diabetes and Digestive and Kidney Diseases | ≈$28.3M |
| 17 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) U19AG024904 | NORTHERN CALIFORNIA INSTITUTE/RES/EDU (CA) | National Institute on Aging | ≈$26.9M |
| 18 | Access for All in ALS (ALL ALS) West Clinical Coordinating Center OT2NS136939 | ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER (AZ) | National Institute of Neurological Disorders and Stroke | ≈$25.3M |
| 19 | NIAID Division of AIDS (DAIDS) Clinical Site Monitoring 75N93021D00 | PPD DEVELOPMENT LP (NC) | National Institute of Allergy and Infectious Diseases | ≈$25.2M |
| 20 | ENABLING NCI CLINICAL & RESEARCH DATA SHARING 75N91019D00 | LEIDOS BIOMEDICAL RESEARCH, INC. (MD) | National Cancer Institute | ≈$25.1M |
| 21 | STRIDES OT2OD027852 | FOUR POINTS TECHNOLOGY, LLC (VA) | NIH Office of the Director | ≈$23.7M |
| 22 | DMID Clinical Research Operations & Management Support (CROMS) 75N93024C00 | TECHNICAL RESOURCES INTERNATIONAL, INC. (MD) | NIH Office of the Director | ≈$23.6M |
| 23 | Access for All in ALS (ALL ALS) East Clinical Coordinating Center OT2NS136938 | MASSACHUSETTS GENERAL HOSPITAL (MA) | National Institute of Neurological Disorders and Stroke | ≈$22.4M |
| 24 | STRIDES OT2OD027852 | FOUR POINTS TECHNOLOGY, LLC (VA) | NIH Office of the Director | ≈$22.4M |
| 25 | All of Us Biobank OT2OD039849 | MAYO CLINIC ROCHESTER (MN) | NIH Office of the Director | ≈$21.9M |
| 26 | Consortium for Advancing Management and Prevention of Cancer in People with HIV UM1CA121947 | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (NY) | National Cancer Institute | ≈$21.5M |
| 27 | NHLBI Community Engagement Technical Assistance Center (CETAC) OT2HL158287 | WESTAT, INC. (MD) | National Heart Lung and Blood Institute | ≈$21.2M |
| 28 | All of Us Biobank OT2OD039849 | MAYO CLINIC ROCHESTER (MN) | NIH Office of the Director | ≈$21.1M |
| 29 | Alzheimer's Prevention Initiative ADAD Colombia Trial Program R01AG086363 | BANNER HEALTH (AZ) | National Institute on Aging | ≈$21M |
| 30 | Statistical and Data Management Center (SDMC), Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG) UM1AI068634 | HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH (MA) | National Institute of Allergy and Infectious Diseases | ≈$20.2M |
| 31 | National Social Life, Health, and Aging Project: Round 5 R01AG048511 | NATIONAL OPINION RESEARCH CENTER (IL) | National Institute on Aging | ≈$18.9M |
| 32 | ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2) U19AG063911 | MAYO CLINIC ROCHESTER (MN) | National Institute on Aging | ≈$18.7M |
| 33 | NIAID/Division of AIDS: Regulatory Support Center 75N93021D00 | TECHNICAL RESOURCES INTERNATIONAL, INC. (MD) | National Institute of Allergy and Infectious Diseases | ≈$18.7M |
| 34 | QCRG Pandemic Response Program U19AI171110 | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (CA) | National Institute of Allergy and Infectious Diseases | ≈$18M |
| 35 | Center for Multiomic Human Brain Cell Atlas UM1MH130994 | SALK INSTITUTE FOR BIOLOGICAL STUDIES (CA) | National Institute of Mental Health | ≈$17.6M |
| 36 | HABS-HD - Core C - Clinical Core U19AG078109 | UNIVERSITY OF NORTH TEXAS HLTH SCI CTR (TX) | National Institute on Aging | ≈$17.5M |
| 37 | HIV Prevention Research Collaboration AI26012001- | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES | National Institute of Allergy and Infectious Diseases | ≈$17.1M |
| 38 | ProCAN: Psychosis Risk Outcomes Compound Assessment Network U01MH137298 | YALE UNIVERSITY (CT) | National Institute of Mental Health | ≈$17.1M |
| 39 | NIA AD/ADRD Health Care Systems Research Collaboratory U54AG063546 | BROWN UNIVERSITY (RI) | National Institute on Aging | ≈$17.1M |
| 40 | Midwest AViDD Center U19AI171954 | UNIVERSITY OF MINNESOTA (MN) | National Institute of Allergy and Infectious Diseases | ≈$17M |
| 41 | The National Health and Aging Trends Study and National Study of Caregiving U01AG032947 | JOHNS HOPKINS UNIVERSITY (MD) | National Institute on Aging | ≈$17M |
| 42 | WashU-VAI Somatic Mosaicism across Human Tissues (SMaHT) Program Genome Characterization Center UM1DA058219 | WASHINGTON UNIVERSITY (MO) | National Institute on Drug Abuse | ≈$16.9M |
| 43 | Center for Antiviral Medicines & Pandemic Preparedness (CAMPP) U19AI171443 | SCRIPPS RESEARCH INSTITUTE, THE (CA) | National Institute of Allergy and Infectious Diseases | ≈$16.9M |
| 44 | Functionally guided adult whole brain cell atlas in human and NHP UM1MH130981 | ALLEN INSTITUTE (WA) | National Institute of Mental Health | ≈$16.8M |
| 45 | DIAN-TU: Tau Next Generation Prevention Trial R01AG068319 | WASHINGTON UNIVERSITY (MO) | National Institute on Aging | ≈$16.5M |
| 46 | A Next Generation Data Infrastructure to Understand Disparities across the Life Course U01AG077280 | UNIVERSITY OF SOUTHERN CALIFORNIA (CA) | National Institute on Aging | ≈$16.5M |
| 47 | Randomized Double Blind, Placebo Controlled, Parallel Group Trial to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease over 18 Months R01AG065248 | COGNITION THERAPEUTICS, INC. (PA) | National Institute on Aging | ≈$16.5M |
| 48 | STRIDES OT2OD027060 | CARAHSOFT TECHNOLOGY CORPORATION (VA) | NIH Office of the Director | ≈$16.5M |
| 49 | SDMC: HIV Prevention Trials Network UM1AI068617 | FRED HUTCHINSON CANCER CENTER (WA) | National Institute of Allergy and Infectious Diseases | ≈$16.3M |
| 50 | The National Dementia Workforce Study U54AG084520 | UNIVERSITY OF MICHIGAN AT ANN ARBOR (MI) | National Institute on Aging | ≈$16.2M |
| 51 | Microbiology and Infectious Diseases Biological Research Repository (MID-BRR) 75N93024C00 | AMERICAN TYPE CULTURE COLLECTION (VA) | National Institute of Allergy and Infectious Diseases | ≈$16M |
| 52 | ECOG-ACRIN NCORP Research Base UG1CA189828 | ECOG-ACRIN MEDICAL RESEARCH FOUNDATION (PA) | National Cancer Institute | ≈$16M |
| 53 | IMPAACT Leadership Group UM1AI068632 | JOHNS HOPKINS UNIVERSITY (MD) | National Institute of Allergy and Infectious Diseases | ≈$16M |
| 54 | Statistical and Data Coordinating Center (SDCC) for Clinical Research in Infectious Diseases 75N93021C00 | THE EMMES COMPANY, LLC (MD) | National Institute of Allergy and Infectious Diseases | ≈$15.8M |
| 55 | Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project U19AG078558 | COLUMBIA UNIVERSITY HEALTH SCIENCES (NY) | National Institute on Aging | ≈$15.7M |
| 56 | Broad-Color: The Genome Center for the Future of All of Us OT2OD038121 | BROAD INSTITUTE, INC. (MA) | NIH Office of the Director | ≈$15.7M |
| 57 | Study of Muscle, Mobility and Aging: SOMMA2 R01AG059416 | CALIFORNIA PACIFIC MED CTR RES INSTITUTE (CA) | National Institute on Aging | ≈$15.6M |
| 58 | Health, Caregiving, Cognition, and Well-being Over the Life Course and Across Multiple Generations RF1AG040213 | UNIVERSITY OF MICHIGAN AT ANN ARBOR (MI) | National Institute on Aging | ≈$15.3M |
| 59 | Environmental influences on Child Health Outcomes (ECHO) Coordinating Center U2COD023375 | DUKE UNIVERSITY (NC) | NIH Office of the Director | ≈$15.3M |
| 60 | DRCR Network UG1EY014231 | JAEB CENTER FOR HEALTH RESEARCH, INC. (FL) | National Eye Institute | ≈$15.1M |
Project titles are official names in the original English. Follow each row's link to the official NIH RePORTER page for the abstract, research categories, and dates. NIH intramural block allocations are excluded, as they are not competitive awards.
Related data
FAQ
What does this page show?
NIH (National Institutes of Health) research projects funded in the most recent fiscal year, ordered by award amount — revealing where the largest U.S. biomedical investments went.
Are individual researchers named?
No. Principal investigator (PI) names and contacts are neither fetched nor shown (PII protection). Only the institution, project title, funding Institute/Center (IC), and amount appear.
What does the amount represent?
The funding (award amount) applied to that project in the fiscal year. Large clinical networks, research centers, and infrastructure programs tend to rank near the top.
I want totals per institution.
For award totals per institution (universities, research bodies), see the "Top NIH grant awardees" ranking. This page shows the largest awards per project; the ranking shows cumulative totals per institution.
What is the source? How can I see more?
Data comes from the official U.S. database NIH RePORTER (API). For each project's detail (abstract, research categories, dates), follow the link in each row to its official RePORTER page.
Sources (primary)
Source: NIH RePORTER (National Institutes of Health, official API, public domain). This site is not an official U.S. government source.