Companies that research, develop, and manufacture drugs, vaccines, and biologics. Drug development involves long timelines and regulatory (FDA) approval, and managing patent expirations (the patent cliff) is a perennial challenge. They are deeply tied to the federal government through emergency R&D, procurement, and stockpiling (e.g., BARDA) and public health insurance.
Featured companies (with cross-source profile)
Read this site's cross-source profile, joining federal contracts (USAspending), SEC filings (EDGAR), and vulnerabilities (CISA KEV).
Public companies in this industry
| Company | Ticker | Exchange | Industry (SIC) |
|---|---|---|---|
| PFIZER INC Explained | PFE | NYSE | Pharmaceutical Preparations |
| 4D Molecular Therapeutics, Inc. | FDMT | Nasdaq | Biological Products, (No Diagnosti... |
| 60 DEGREES PHARMACEUTICALS, INC. | SXTP | Nasdaq | Pharmaceutical Preparations |
| Aardvark Therapeutics, Inc. | AARD | Nasdaq | Pharmaceutical Preparations |
| ABBOTT LABORATORIES | ABT | NYSE | Pharmaceutical Preparations |
| AbbVie Inc. | ABBV | NYSE | Pharmaceutical Preparations |
| AbCellera Biologics Inc. | ABCL | Nasdaq | Pharmaceutical Preparations |
| ABEONA THERAPEUTICS INC. | ABEO | Nasdaq | Pharmaceutical Preparations |
| Abivax S.A. | ABVX | OTC | Pharmaceutical Preparations |
| Abpro Holdings, Inc. | ABPO | OTC | Biological Products, (No Diagnosti... |
| Absci Corp | ABSI | Nasdaq | Services-Commercial Physical & Bio... |
| ABVC BIOPHARMA, INC. | ABVC | Nasdaq | Pharmaceutical Preparations |
| AC Immune SA | ACIU | Nasdaq | Pharmaceutical Preparations |
| ACADIA PHARMACEUTICALS INC | ACAD | Nasdaq | Pharmaceutical Preparations |
| Accustem Sciences Inc. | ACUT | OTC | Pharmaceutical Preparations |
| ACHIEVE LIFE SCIENCES, INC. | ACHV | Nasdaq | In Vitro & In Vivo Diagnostic Subs... |
| Aclaris Therapeutics, Inc. | ACRS | Nasdaq | Pharmaceutical Preparations |
| Acrivon Therapeutics, Inc. | ACRV | Nasdaq | Pharmaceutical Preparations |
| Actinium Pharmaceuticals, Inc. | ATNM | NYSE | Pharmaceutical Preparations |
| ACTUATE THERAPEUTICS, INC. | ACTU | Nasdaq | Pharmaceutical Preparations |
| Acumen Pharmaceuticals, Inc. | ABOS | Nasdaq | Biological Products, (No Diagnosti... |
| Acurx Pharmaceuticals, Inc. | ACXP | Nasdaq | Pharmaceutical Preparations |
| Adagene Inc. | ADAG | Nasdaq | Pharmaceutical Preparations |
| Adaptimmune Therapeutics PLC | ADAPY | — | Biological Products, (No Diagnosti... |
| ADAPTIN BIO, INC. | APTN | OTC | Biological Products, (No Diagnosti... |
| Adaptive Biotechnologies Corp | ADPT | Nasdaq | Biological Products, (No Diagnosti... |
| Adastra Holdings Ltd. | XTXXF | OTC | Pharmaceutical Preparations |
| ADC Therapeutics SA | ADCT | NYSE | Pharmaceutical Preparations |
| Addex Therapeutics Ltd. | ADXN | Nasdaq | Pharmaceutical Preparations |
| Adia Nutrition, Inc. | ADIA | OTC | Medicinal Chemicals & Botanical Pr... |
| ADIAL PHARMACEUTICALS, INC. | ADIL | Nasdaq | Pharmaceutical Preparations |
| Adicet Bio, Inc. | ACET | Nasdaq | Pharmaceutical Preparations |
| Aditxt, Inc. | ADTX | Nasdaq | Pharmaceutical Preparations |
| Adlai Nortye Ltd. | ANL | Nasdaq | Pharmaceutical Preparations |
| ADMA BIOLOGICS, INC. | ADMA | Nasdaq | Biological Products, (No Diagnosti... |
| AEON Biopharma, Inc. | AEON | NYSE | Pharmaceutical Preparations |
| Agentix Corp. | AGTX | OTC | Biological Products, (No Diagnosti... |
| AGENUS INC | AGEN | Nasdaq | Biological Products, (No Diagnosti... |
| AGIOS PHARMACEUTICALS, INC. | AGIO | Nasdaq | Pharmaceutical Preparations |
| Agomab Therapeutics NV | AGMB | Nasdaq | Biological Products, (No Diagnosti... |
| AIBOTICS, INC. | AIBT | OTC | Medicinal Chemicals & Botanical Pr... |
| AIM ImmunoTech Inc. | AIM | NYSE | Biological Products, (No Diagnosti... |
| AKANDA CORP. | AKAN | Nasdaq | Medicinal Chemicals & Botanical Pr... |
| Akari Therapeutics Plc | AKTX | Nasdaq | Pharmaceutical Preparations |
| Akebia Therapeutics, Inc. | AKBA | Nasdaq | Pharmaceutical Preparations |
| Aktis Oncology, Inc. | AKTS | Nasdaq | Pharmaceutical Preparations |
| Alaunos Therapeutics, Inc. | TCRT | Nasdaq | Pharmaceutical Preparations |
| Aldeyra Therapeutics, Inc. | ALDX | Nasdaq | Pharmaceutical Preparations |
| Alector, Inc. | ALEC | Nasdaq | Biological Products, (No Diagnosti... |
| Algernon Health Inc. | AGNPF | OTC | Pharmaceutical Preparations |
| Aligos Therapeutics, Inc. | ALGS | Nasdaq | Biological Products, (No Diagnosti... |
| Alkermes plc. | ALKS | Nasdaq | Pharmaceutical Preparations |
| Allarity Therapeutics, Inc. | ALLR | Nasdaq | Pharmaceutical Preparations |
| Allogene Therapeutics, Inc. | ALLO | Nasdaq | Biological Products, (No Diagnosti... |
| ALNYLAM PHARMACEUTICALS, INC. | ALNY | Nasdaq | Pharmaceutical Preparations |
| Alpha Cognition Inc. | ACOG | Nasdaq | Biological Products, (No Diagnosti... |
| Alpha Teknova, Inc. | TKNO | Nasdaq | In Vitro & In Vivo Diagnostic Subs... |
| Altamira Therapeutics Ltd. | CYTOF | OTC | Pharmaceutical Preparations |
| ALTERITY THERAPEUTICS LTD | ATHE | OTC | Pharmaceutical Preparations |
| Altimmune, Inc. | ALT | Nasdaq | Pharmaceutical Preparations |
FAQ
How is it tied to government?
Beyond FDA approval, it links deeply through emergency R&D, procurement, and stockpiling (e.g., BARDA) and public health insurance (Medicare).
Which companies are representative?
Pfizer, Merck, Johnson & Johnson, Amgen, and Gilead.
What is the patent cliff?
When a flagship drug loses patent protection, generics enter and sales fall sharply; replenishing the pipeline is a perennial challenge.
Sources (primary)
Organized from the SEC's industry classification (SIC). Classification reflects the issuer's reported principal business and may differ from a company's actual mix.
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