$2,057,137 Cross-Directorate Activities

NSF grant ~$2.06M: how does the brain decide what to say next? Decoding conversational speech with LLMs (USC)

University of Southern California California Started Jul 2026

A ~$2.06 million ($2,057,137) NSF grant to the University of Southern California. Subjects hold weekly conversations for a full year while their brain activity is recorded with fMRI; large language models are then mapped onto that activity to reveal how the brain drives a conversation forward. The resulting dataset will be shared widely as a community benchmark.

Grant overview (primary data)

  • Award amount$2,057,137
  • RecipientUniversity of Southern California (California)
  • ProgramCross-Directorate Activities
  • Period2026-07-01 〜 2031-06-30
  • FunderU.S. National Science Foundation (NSF) / NSF

Key points

  • Recipient: University of Southern California; ~$2.06M ($2,057,137); July 2026–June 2031 (5 years)
  • A CRCNS (computational neuroscience) proposal targeting the understudied side of language: production, not comprehension
  • Longitudinal fMRI dataset: the same pairs converse weekly for a year, capturing accumulated conversational memory
  • LLM internals are mapped onto brain activity to identify the neural signatures that drive the next utterance
  • The dataset will be shared widely — a benchmark asset for naturalistic-dialogue neuroscience

We use language to organize thought, externalize ideas, and explain reasoning — yet how the brain decides what to say next has remained a blank spot in neuroscience. Comprehension has been studied extensively; production has not, largely because natural conversation is hard to recreate in a laboratory.

This project's novelty is a longitudinal design that sidesteps the problem: the same pairs of participants converse weekly for a year, so the accumulating shared memory that real conversation rests on is captured along with the dialogue itself.

1Using AI as an instrument, not a subject

The second key move is using AI as an instrument rather than a subject. LLMs are the first generation of models that can turn natural-language input into meaningful responses, and their internal representations serve as concrete hypotheses for the computation of "composing a reply." Aligning those representations with fMRI signals gives researchers a ruler for locating where and how that computation unfolds in the brain.

AI is used to read the brain; what is learned feeds back into the design of future AI — a bootstrapping loop emblematic of where the field now stands.

2A public dataset as a deliverable

Just as important, the deliverable is not only papers but a public dataset. Naturalistic conversational fMRI data is extremely expensive to collect; shared, it lets researchers worldwide test hypotheses on common ground. It is a textbook case of an NSF award doubling as investment in field-wide research infrastructure.

Why it matters

Understanding speech production underpins more human-like conversational AI, assistive technology for speech disorders, and brain–machine interfaces. The two-way cycle — measuring the brain with AI, refining AI with brain science — plus the open-dataset infrastructure angle make this a useful reference point for the AI × neuroscience trend.

FAQ

Why use LLMs to study the brain?
LLMs are the first models that generate meaningful responses from natural language, so their internal representations are concrete hypotheses for how a reply is composed. Aligning them with brain activity lets researchers quantify the neural processes that drive conversation.
What is new here?
Language neuroscience has focused on comprehension; production is largely unexplained. The year-long weekly-dialogue design captures natural conversation and its accumulated shared memory — something one-off lab sessions cannot.
Who can use the results?
The fMRI dataset is to be shared widely with the research community as a resource and benchmark. Making such costly naturalistic data a common asset is itself an investment in the whole field.

Sources (primary)

Source: NSF Award Search (U.S. National Science Foundation, public domain). Amounts are the obligated amount. For privacy, we do not handle principal investigator names.

#AI#NSF#Research grant#Neuroscience#LLM#fMRI#USC
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